ATM-ATR inhibitor KU-60019, Purity ≥98%

Synonym: 925701-49-1, 925701-46-8; KU60019; KU-60019; ATM-ATR inhibitor

CAS Number: 925701-49-1, 925701-46-8

Product Size

10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

KU-60019, soluble in warmed DMSO and insoluble in water and ethanol, interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells. It targets ATM.

Molecular Weight

547.7

Molecular Formula

C₃₀H₃₃N₃O₅S

Targets

ATM: 6.3 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 18 mg/mL (32.86 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

KU-60019 is employed to study the selective inhibition of ATM kinase in cancer therapy and radiosensitization.

Storage

Store at -20ºC.