ATM-ATR inhibitor VE-821, Purity ≥98%

Synonym: 1232410-49-9; VE821; ATM-ATR inhibitor

CAS Number: 1232410-49-9
Compound CID: 51000408

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

VE-821, soluble in DMSO and insoluble in ethanol and water, interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells. It targets ATR.

Molecular Weight

368.4

Molecular Formula

C₁₈H₁₆N₄O₃S

Targets

ATR: 13 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 65 mg/mL (176.43 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

VE-821 is used to investigate ATR kinase inhibition and its potential in enhancing the sensitivity of cancer cells to DNA-damaging agents.

Storage

Store at -20ºC.