ATPase inhibitor Bafilomycin A1, Purity ≥98%

Synonym: 88899-55-2; ATPase inhibitor

MDL: MFCD06795130
CAS Number: 88899-55-2
Compound CID: 6436223

Product Size

0.5 mg; 1 mg; 2 mg; 5 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bafilomycin A1, soluble in DMSO and insoluble in ethanol and water, specifically hinders the activity of ATPase enzymes, thereby disrupting the process of ATP hydrolysis, which is critical for energy conversion and cellular functions. It targets H+-ATPase.

Molecular Weight

622.84

Molecular Formula

C₃₅H₅₈O₉

Targets

H+-ATPase: 0.44 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 6 mg/mL (9.63 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Bafilomycin A1 is used in cell biology to study vacuolar-type H⁺-ATPase function and its involvement in intracellular pH regulation and autophagy.