Properties
Description
Sodium orthovanadate, soluble in water and insoluble in DMSO and ethanol, specifically hinders the activity of ATPase enzymes, thereby disrupting the process of ATP hydrolysis, which is critical for energy conversion and cellular functions. It targets (Na,K)-ATPase and phosphatase.
Targets
(Na,K)-ATPase: 40 nM; Phosphatase: 10 μM
Solubility
DMSO: Insoluble; Water: 32 mg/mL (173.99 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Sodium orthovanadate is an ATPase inhibitor utilized in studies exploring the inhibition of phosphatases and the modulation of cellular ATPase activity.