Aurora kinase inhibitor AMG 900, Purity ≥98%

Synonym: 945595-80-2; AMG-900; AMG900; Aurora kinase inhibitor

CAS Number: 945595-80-2

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AMG 900, soluble in DMSO and insoluble in ethanol and water, is an Aurora kinase inhibitor that disrupts cell division processes. It targets Aurora A, AuroraB, AuroraC, and JNK2.

Molecular Weight

503.6

Molecular Formula

C₂₈H₂₁N₇OS

Targets

Aurora A: 5 nM; AuroraB: 4 nM; AuroraC: 1 nM; JNK2: 520 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 90 mg/mL (178.71 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AMG 900 is employed to investigate its role in inhibiting Aurora kinases A, B, and C, affecting mitosis and cancer cell proliferation.

Storage

Store at -20ºC.