Aurora kinase inhibitor AZD1152-HQPA, Purity ≥98%

Synonym: 722544-51-6; Barasertib; Aurora kinase inhibitor

CAS Number: 722544-51-6

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD1152-HQPA, soluble in DMSO and ethanol and insoluble in water, is an Aurora kinase inhibitor that disrupts cell division processes. It targets Aurora A and Aurora B.

Molecular Weight

507.7

Molecular Formula

C₂₆H₃₀FN₇O₃

Targets

Aurora A: 1368 nM; Aurora B: 0.37 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 93 mg/mL (183.23 mM); Water: Insoluble; Ethanol: 3 mg/mL (5.91 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD1152-HQPA is used to study its selective inhibition of Aurora B kinase in mitosis regulation.