Aurora kinase inhibitor CCT137690, Purity ≥98%

Synonym: 1095382-05-0; CCT137690; CCT 137690; CCT-137690; 3-((4-(6-Bromo-2-(4-(4-methylpiperazin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-5-methylisoxazole; 6-Bromo-7-{4-[(5-Methylisoxazol-3-Yl)methyl]piperazin-1-Yl}-2-[4-(4-Methylpiperazin-1-Yl)phenyl]-1H-Imidazo[4,5-B]pyridine; Aurora kinase inhibitor

CAS Number: 1095382-05-0
Compound CID: 25154041

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CCT137690, soluble in DMSO and insoluble in ethanol and water, is an Aurora kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, and Aurora C.

Molecular Weight

551.5

Molecular Formula

C₂₆H₃₁BrN₈O

Targets

Aurora A: 15 nM; Aurora B: 25 nM; Aurora C: 15 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 4 mg/mL (7.25 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

CCT137690 is useful in research focusing on the inhibition of Aurora B kinase and its impact on cancer cell proliferation.