Aurora kinase inhibitor Hesperadin, Purity ≥98%

Synonym: Hesperadin; 422513-13-1; hesperadine; UNII-PTR491OS14; CHEBI:70726; TCMDC-135395; CHEMBL514409; Aurora kinase inhibitor

MDL: MFCD18074526
CAS Number: 422513-13-1
Compound CID: 135421442

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hesperadin, soluble in DMSO and insoluble in ethanol and water, is an Aurora kinase inhibitor that disrupts cell division processes. It targets Aurora B (human) and TbAUK1.

Molecular Weight

516.7

Molecular Formula

C₂₉H₃₂N₄O₃S

Targets

Aurora B (Human): 250 nM; TbAUK1: 40 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 100 mg/mL (193.55 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Hesperadin is employed to study the effects of Aurora B kinase inhibition on chromosome alignment and segregation.