Aurora kinase inhibitor Reversine, Purity ≥98%

Synonym: 656820-32-5; Reversine; 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine; CHEMBL188343; CHEBI:70723; Aurora kinase inhibitor

CAS Number: 656820-32-5
Compound CID: 210332

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Reversine, soluble in warmed DMSO and insoluble in water and ethanol, is an Aurora kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, Aurora C, and human A3 adenosine receptor.

Molecular Weight

393.5

Molecular Formula

C₂₁H₂₇N₇O

Targets

Aurora A: 12 nM; Aurora B: 13 nM; Aurora C: 20 nM; Human A3 adenosine receptor: 0.66 μM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 4 mg/mL (10.17 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Reversine is used to study its role as a multi-kinase inhibitor affecting cell differentiation and proliferation.

Storage

Store at -20ºC.