Aurora kinase inhibitor SNS-314, Purity ≥98%

Synonym: SNS-314 Mesylate; 1146618-41-8; SNS 314 mesylate; SNS-314 (mesylate); KGW32FDY3U; 1-(3-Chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea; Methanesulfonic acid; Aurora kinase inhibitor

CAS Number: 1146618-41-8
Compound CID: 24995523

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SNS-314, soluble in warmed DMSO and warmed ethanol and insoluble in water, is an Aurora kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, and Aurora C.

Molecular Weight

527

Molecular Formula

C₁₈H₁₅ClN₆OS₂.CH₄O₃S

Targets

Aurora A: 9 nM; Aurora B: 31 nM; Aurora C: 3 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 80 mg/mL (151.79 mM); Water: Insoluble; Warmed ethanol: 1 mg/mL (1.89 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SNS-314 can be used to research the triple inhibition of Aurora kinases A, B, and C in oncology.

Storage

Store at -20ºC.