Aurora kinase inhibitor TC-S 7010, Purity ≥98%

Synonym: Aurora A Inhibitor I; 1158838-45-9; TC-S 7010; N-(2-Chlorophenyl)-4-((2-((4-(2-(4-ethylpiperazin-1-yl)-2-oxoethyl)phenyl)amino)-5-fluoropyrimidin-4-yl)amino)benzamide; 2,4-Bisanilinopyrimidine, 10; TCS7010; Aurora-A-inhibitor-I; Aurora kinase inhibitor

CAS Number: 1158838-45-9
Compound CID: 44139710

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TC-S 7010, soluble in DMSO and insoluble in ethanol and water, is an Aurora kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, and Aurora C.

Molecular Weight

588.1

Molecular Formula

C₃₁H₃₁ClFN₇O₂

Targets

Aurora A: 3.4 nM; Aurora B: 3.4 nM; Aurora C: 432 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 105 mg/mL (178.54 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

TC-S 7010 can be applied to investigate the inhibition of Aurora kinases and its impact on cellular proliferation.