Autophagy inhibitor, Autophinib, Purity ≥98%

Synonym: 1644443-47-9; ZB1499; CCG-267994; CS-7665; AC-35537; BS-16113; HY-101920; F20853; 6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine; Autophagy inhibitor

CAS Number: 1644443-47-9
Compound CID: 129626605

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Autophinib, soluble in DMSO and insoluble in water and ethanol, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy. The molecular weight of the compound is 346.731, and its molecular formula is C₁₄H₁₁ClN₆O₃. It targets the Vps34.

Molecular Weight

346.731

Molecular Formula

C₁₄H₁₁ClN₆O₃

Targets

Vps34

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 63 mg/mL (181.7 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Autophinib plays a key role in targeting cancer cells that rely on autophagy for growth and survival.