Autophagy inhibitor, EN6, Purity ≥98%

Synonym: 1808714-73-9; EN6; EN-6; EN 6; 1-(2-Fluorophenyl)-N-[4-fluoro-3-(prop-2-enoylamino)phenyl]pyrazole-4-carboxamide; Autophagy inhibitor

MDL: MFCD31665468
CAS Number: 1808714-73-9
Compound CID: 99640033

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

EN6, soluble in DMSO and insoluble in water and ethanol, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy. The molecular weight of the compound is 368.34, and its molecular formula is C₁₉H₁₄F₂N₄O₂.

Molecular Weight

368.34

Molecular Formula

C₁₉H₁₄F₂N₄O₂

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 68 mg/mL (184.61 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

EN6 displays the significant potential to act as an effective inhibitor of the protein kinase mTOR, which plays a crucial role in cell growth and metabolism.