Autophagy inhibitor, ROC-325, Purity ≥98%

Synonym: 1859141-26-6; ROC 325; ROC325; 1-[2-[2-[(7-Chloroquinolin-4-yl)amino]ethyl-methylamino]ethylamino]-4-methylthioxanthen-9-one; Autophagy inhibitor

CAS Number: 1859141-26-6
Compound CID: 129626603

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ROC-325, soluble in DMSO and ethanol and insoluble in water, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy. The molecular weight of the compound is 503.06, and its molecular formula is C₂₈H₂₇ClN₄OS.

Molecular Weight

503.06

Molecular Formula

C₂₈H₂₇ClN₄OS

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 3 mg/mL (5.96 mM); Water: insoluble; Ethanol: 3 mg/mL (5.96 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

ROC-325 can be studied extensively for its potential therapeutic applications in the treatment of various cancers, particularly those with aberrant PI3K signaling, and may also have applications in metabolic diseases.