Autophagy inhibitor, SBC-115076, Purity ≥98%

Synonym: 489415-96-5; SBC 115076; SBC115076; (4E)-4-[Hydroxy-(3-methyl-4-phenylmethoxyphenyl)methylidene]-1-(3-morpholin-4-ylpropyl)-5-pyridin-4-ylpyrrolidine-2,3-dione; Autophagy inhibitor

CAS Number: 489415-96-5
Compound CID: 5734410

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SBC-115076, soluble in DMSO and insoluble in water and ethanol, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy. The molecular weight of the compound is 527.61, and its molecular formula is C₃₁H₃₃N₃O₅.

Molecular Weight

527.61

Molecular Formula

C₃₁H₃₃N₃O₅

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 28 mg/mL (53.06 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 45% PEG 300 + ddH₂O, 6 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

SBC-115076 can be studied extensively for its potential therapeutic applications in the treatment of type 2 diabetes by enhancing insulin sensitivity and glucose uptake.