Autophagy inhibitor, STF-62247, Purity ≥98%

Synonym: 315702-99-9; STF62247; Autophagy inducer, STF 62247; 4-(Pyridin-4-yl)-N-(m-tolyl)thiazol-2-amine; N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine; Autophagy inhibitor

CAS Number: 315702-99-9
Compound CID: 704473

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

STF-62247, soluble in DMSO and ethanol and insoluble in water, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy. The molecular weight of the compound is 267.4, and its molecular formula is C₁₅H₁₃N₃S.

Molecular Weight

267.4

Molecular Formula

C₁₅H₁₃N₃S

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 47 mg/mL (175.8 mM); Water: insoluble; Ethanol: 3 mg/mL (11.22 mM); In vivo: 1% DMSO + 30% polyethylene glycol + 1% Tween 80, 6 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

STF-62247 can be studied extensively for its potential therapeutic applications in the treatment of neurodegenerative diseases, diabetes, and certain types of cancer by modulating GSK3 activity.