Autophagy inhibitor, Telaglenastat, Purity ≥98%

Synonym: 1439399-58-2; CB839; CB 839; N-[6-[4-[5-[(2-Pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide; Autophagy inhibitor

MDL: MFCD28167826
CAS Number: 1439399-58-2
Compound CID: 71577426

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Telaglenastat, soluble in DMSO and insoluble in water and ethanol, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy. The molecular weight of the compound is 571.57, and its molecular formula is C₂₆H₂₄F₃N₇O₃S. It targets the glutaminase.

Molecular Weight

571.57

Molecular Formula

C₂₆H₂₄F₃N₇O₃S

Targets

Glutaminase

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO (warmed): 97 mg/mL (169.7 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + corn oil, 2 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Telaglenastat can be studied extensively for its potential therapeutic applications in the treatment of tumors that rely heavily on glutamine for growth and survival.