Properties
Description
BAY-u 3405, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets hDP2, hDP2, and hTP.
Molecular Formula
C21H21FN2O4S
Targets
hDP2: 113 nM; hDP2: 33.4 μM; hTP: 14 nM
Solubility
DMSO: 76 mg/mL (182.48 mM); Water: insoluble; Ethanol: 76 mg/mL
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BAY-u 3405 can be used for its ability to inhibit ovalbumin-induced airway eosinophil infiltration and mucus cell hyperplasia.
Storage
Store at -20°C, and keep desiccated.
