Bcl-2 activator BAM7, Purity ≥98%

Synonym: 331244-89-4; BAM7; BAM 7; BAM-7; BAX Activator Molecule 7; (E)-4-(2-(2-Ethoxyphenyl)hydrazono)-3-methyl-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5(4H)-one; Bcl-2 activator

CAS Number: 331244-89-4
Compound CID: 3101542

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BAM7, soluble in DMSO and insoluble in ethanol and water, promotes apoptosis by activating pro-apoptotic Bcl-2 family members or inhibiting anti-apoptotic members. It targets Bax.

Molecular Weight

405.47

Molecular Formula

C₂₁H₁₉N₅O₂S

Targets

Bax: 3.3 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 2 mg/mL (4.93 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

BAM7 is used in research to specifically activate the pro-apoptotic protein BAX, enabling the study of direct induction of apoptosis in various cancer models.