Bcl-2 inhibitor A-385358, Purity ≥98%

Synonym: 406228-55-5; A-385358; CHEMBL192571; N-[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-(4,4-dimethylpiperidin-1-yl)benzamide; Phenylpiperidine, 1a; SCHEMBL681275; A 385358; N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide; Bcl-2 inhibitor

CAS Number: 406228-55-5
Compound CID: 11556440

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

A-385358 specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells.

Molecular Weight

639.83

Molecular Formula

C₃₂H₄₁N₅O₅S₂

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

A-385358 can be used to explore selective inhibition of the Bcl-XL protein, providing insights into anti-apoptotic mechanisms.