Bcl-2 inhibitor AZD-4320, Purity ≥98%

Synonym: 1357576-48-7; AZD4320; AZD-4320; UNII-LH1ZTY91OR; LH1ZTY91OR; 4-(4-((R)-(4'-Chloro(1,1'-biphenyl)-2-yl)hydroxymethyl)-1-piperidinyl)-N-((4-(((1R)-3-((2-hydroxyethyl)methylamino)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide; 4-(4-((R)-(4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)-N-(4-((R)-4-((2-hydroxyethyl)(methyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide; Bcl-2 inhibitor

CAS Number: 1357576-48-7
Compound CID: 86661883

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD-4320 specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells.

Molecular Weight

945.52

Molecular Formula

C₄₅H₄₈ClF₃N₄O₇S₃

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AZD-4320 can be used to investigate the dual inhibition of Bcl-2 and Bcl-XL in cancer therapy.

Storage

Store at -20ºC.