Bcl-2 inhibitor HA14-1, Purity ≥98%

Synonym: 65673-63-4; Ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate; Bcl-2 inhibitor

MDL: MFCD00218213
CAS Number: 65673-63-4
Compound CID: 3549

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

HA14-1, soluble in DMSO and ethanol and insoluble in water, specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells. It targets Bcl-2.

Molecular Weight

409.2

Molecular Formula

C₁₇H₁₇BrN₂O₅

Targets

Bcl-2: 9 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 80 mg/mL (195.48 mM); Water: Insoluble; Ethanol: 80 mg/mL (195.48 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

HA14-1 induces apoptosis in cancer cells by interfering with BCL-2’s anti-apoptotic function.

Storage

Store at -20ºC.