Bcl-2 inhibitor Marinopyrrole A, Purity ≥98%

Synonym: 1227962-62-0; Marinopyrrole A; Maritoclax; (-)-marinopyrrole A; 1010732-14-5; (-)-Maritoclax; Marinopyrrole A (Maritoclax); [4,5-dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(2-hydroxyphenyl)methanone; Bcl-2 inhibitor

CAS Number: 1227962-62-0
Compound CID: 24797083

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

Marinopyrrole A, soluble in DMSO and ethanol and insoluble in water, specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells.

Molecular Weight

510.15

Molecular Formula

C₂₂H₁₂Cl₄N₂O₄

Form

Lyophilized powder

Purity

Solubility

DMSO: 99 mg/mL (194.06 mM); Water: Insoluble; Ethanol: 45 mg/mL (88.2 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Marinopyrrole A can be used to study the inhibition of the Bcl-XL protein in cancer cell lines.