Bcl-2 inhibitor Obatoclax mesylate, Purity ≥98%

Synonym: 803712-79-0; Obatoclax mesylate; Obatoclax mesilate; Obatoclax (Mesylate); 2-(2-((3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-1H-indole methanesulfonate; Bcl-2 inhibitor

MDL: MFCD18074508
CAS Number: 803712-79-0
Compound CID: 16681698

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Obatoclax mesylate, soluble in DMSO and insoluble in ethanol and water, specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells. It targets Bcl-2.

Molecular Weight

413.5

Molecular Formula

C₂₀H₁₉N₃O.CH₄O₃S

Targets

Bcl-2

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (195.89 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Obatoclax mesylate has shown potential in overcoming resistance to apoptosis in cancer cells.

Storage

Store at -20ºC.