Bcl-2 inhibitor S55746, Purity ≥98%

Synonym: 1448584-12-0; 1448525-91-4; s55746; BCL201; BCL-201; UNII-W93257I68I; N-(4-Hydroxyphenyl)-3-[6-[(3S)-3-(morpholin-4-ylmethyl)-3,4-dihydro-1H-isoquinoline-2-carbonyl]-1,3-benzodioxol-5-yl]-N-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide; Bcl-2 inhibitor

CAS Number: 1448584-12-0
Compound CID: 71654876

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

S55746, soluble in DMSO and insoluble in ethanol and water, specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells.

Molecular Weight

710.82

Molecular Formula

C₄₃H₄₂N₄O₆

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 88 mg/mL (123.8 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

S55746 is employed to study its function as a selective BCL-2 inhibitor, aiding in the development of new treatments for BCL-2-dependent cancers.

Storage

Store at -20ºC.