Bcr-Abl inhibitor AMN-107, Purity ≥98%

Synonym: 641571-10-0; Bcr-Abl inhibitor; AMN107

MDL: MFCD09833716
CAS Number: 641571-10-0
Compound CID: 644241

Product Size

100 mg; 200 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AMN-107, soluble in DMSO and insoluble in ethanol and water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Bcr-Abl (Murine myeloid progenitor cells).

Molecular Weight

529.5

Molecular Formula

C₂₈H₂₂F₃N₇O

Targets

Bcr-Abl (Murine myeloid progenitor cells): <30 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 26 mg/mL (49.09 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AMN-107 inhibits Bcr-Abl, focusing on treating drug-resistant chronic myeloid leukemia.