Bcr-Abl inhibitor Asciminib, Purity ≥98%

Synonym: 1492952-76-7; Bcr-Abl inhibitor; ABL001; ABL 001; ABL-001

CAS Number: 1492952-76-7
Compound CID: 72165228

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Asciminib, soluble in DMSO and ethanol, specifically inhibits the activity of the Bcr-Abl tyrosine kinase.

Molecular Weight

449.84

Molecular Formula

C₂₀H₁₈ClF₂N₅O₃

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 76 mg/mL (168.94 mM); Ethanol: 76 mg/mL (168.94 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Asciminib is integral to researching new treatment approaches for chronic myeloid leukemia (CML) through specific targeting of the Bcr-Abl1 fusion protein.