AT9283, soluble in DMSO and ethanol and insoluble in water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Aurora A, JAK2, Abl (Q252H), Abl1 (T315I), AuroraB, DRAK1, FGFR1, FGFR1 (V561M), FGFR2, FGFR2 (N549H), and FGFR3.
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AT9283 serves as a research compound to investigate inhibition of multiple kinases including JAK2, with applications in cancer therapy.
Storage
Store at -20ºC.
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