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Bcr-Abl inhibitor AZD0530, Purity ≥98%
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Cat. No.: X24-06-ZQ350

Bcr-Abl inhibitor AZD0530, Purity ≥98%

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Synonym: 379231-04-6; Bcr-Abl inhibitor; AZD-0530

  • MDL: MFCD09832698
  • CAS Number: 379231-04-6
  • Compound CID: 10302451
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Product Size
10 mg; 25 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZD0530, soluble in warmed DMSO and ethanol and insoluble in water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets c-YES, LCK, BLK, c-Kit, c-Src, CDK2, CSK, EGFR, EGFR (L858R), EGFR (L861Q), and EphA2.
Molecular Weight
542
Molecular Formula
C27H32ClN5O5
Targets
c-YES: 4 nM; LCK: <4 nM; BLK: 11 nM; c-Kit: 200 nM; c-Src: 2.7 nM; CDK2: 10 nM; CSK: >1 μM; EGFR: 66 μM; EGFR (L858R): 5 μM; EGFR (L861Q): 4 μM; EphA2: 236 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 34 mg/mL (62.73 mM); Water: Insoluble; Ethanol: 30 mg/mL (55.35 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD0530 is utilized in research to target and inhibit Bcr-Abl tyrosine kinases, providing insights into mechanisms of leukemia treatment.
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