Properties
Description
CHMFL-ABL-121 specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets ABL wt and ABL-T315I.
Molecular Formula
C30H31F3N6OS
Targets
ABL wt: 2 nM; ABL-T315I: 0.2 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
CHMFL-ABL-121 targets the Bcr-Abl fusion kinase, providing insights for developing treatments for leukemia.