Bcr-Abl inhibitor GNF 2, Purity ≥98%

Synonym: 778270-11-4; Bcr-Abl inhibitor; GNF2; GNF-2

MDL: MFCD09265253
CAS Number: 778270-11-4
Compound CID: 5311510

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GNF 2, soluble in DMSO and insoluble in ethanol and water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Bcr-Abl (K562 cell line) and Bcr-Abl (SUP-B15 cell line).

Molecular Weight

374.3

Molecular Formula

C₁₈H₁₃F₃N₄O₂

Targets

Bcr-Abl (K562 cell line): 273 nM; Bcr-Abl (SUP-B15 cell line): 268 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 67 mg/mL (178.99 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GNF 2 inhibits Bcr-Abl, useful in chronic myeloid leukemia studies.