Bcr-Abl inhibitor INNO-406, Purity ≥98%

Synonym: 859212-16-1; Bcr-Abl inhibitor; NS-187

CAS Number: 859212-16-1
Compound CID: 11387605

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

INNO-406, soluble in DMSO and insoluble in ethanol and water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Abl and Lyn.

Molecular Weight

576.6

Molecular Formula

C₃₀H₃₁F₃N₈O

Targets

Abl: 5.8 nM; Lyn: 19 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 92 mg/mL (159.55 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

INNO-406 serves as a research compound for understanding resistance mechanisms in CML treatment through its multitargeting effects on Bcr-Abl and Lyn kinases.