Properties
Description
PD173955, soluble in warmed DMSO and insoluble in water and ethanol, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Bcr-Abl and Src.
Molecular Formula
C21H16Cl2N4OS
Targets
Bcr-Abl: 1-2 nM; Src: 22 nM
Solubility
Warmed DMSO: 13 mg/mL (29.32 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PD173955 targets Bcr-Abl, investigated for its efficacy in treating leukemia.