Properties
Description
Radotinib, soluble in DMSO and insoluble in ethanol and water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets BCR-ABL1.
Molecular Formula
C27H21F3N8O
Solubility
DMSO: 94 mg/mL (177.19 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Radotinib is explored for its ability to inhibit Bcr-Abl kinase, offering insights into therapeutic approaches for chronic myeloid leukemia.