Bcr-Abl inhibitor WP1130, Purity ≥98%

Synonym: 856243-80-6; Bcr-Abl inhibitor; WP-1130; Degrasyn

MDL: MFCD18839228
CAS Number: 856243-80-6
Compound CID: 11222830

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WP1130, soluble in DMSO and ethanol and insoluble in water, specifically inhibits the activity of the Bcr-Abl tyrosine kinase. It targets Bcr-Abl and DUB.

Molecular Weight

384.3

Molecular Formula

C₁₉H₁₈BrN₃O

Targets

Bcr-Abl: 1.8 μM; DUB

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 73 mg/mL (189.96 mM); Water: Insoluble; Ethanol: 17 mg/mL (44.24 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

WP1130 is used in the investigation of Bcr-Abl inhibition and its impact on signal transduction in leukemia cells.