BIBF0775

Synonym: 334951-90-5; (Z)-N-Ethyl-N-methyl-2-oxo-3-(phenyl((4-(piperidin-1-ylmethyl)phenyl)amino)methylene)indoline-6-carboxamide

CAS Number: 334951-90-5
PubChem CID: 135837779

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BIBF0775, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway.

Molecular Weight

494.639

Molecular Formula

C₃₁H₃₄N₄O₂

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 13 mg/mL (26.28 mM); Water: insoluble; Ethanol: 2 mg/mL (4.04 mM)

Applications

BIBF0775 can be used for its anti-cancer effects in part through the inhibition of angiogenesis, the process by which new blood vessels are formed to supply nutrients and oxygen to tumors.