Properties
Description
BIBF0775, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway.
Molecular Formula
C31H34N4O2
Solubility
DMSO: 13 mg/mL (26.28 mM); Water: insoluble; Ethanol: 2 mg/mL (4.04 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BIBF0775 can be used for its anti-cancer effects in part through the inhibition of angiogenesis, the process by which new blood vessels are formed to supply nutrients and oxygen to tumors.
Storage
Store at -20℃, and keep desiccated.
