Bindarit, Purity ≥98%

Synonym: 130641-38-2; AF2838; AF 2838; AF-2838; 2-[(1-Benzylindazol-3-yl)methoxy]-2-methylpropanoic acid; Propanoic acid, 2-methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]-; 2-[(1-Benzylindazol-3-yl)methoxy]-2-methylpropanoic acid

CAS Number: 130641-38-2
Compound CID: 71354

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Bindarit, soluble in DMSO and ethanol and insoluble in water, is an anti-inflammatory small molecule that modulates the NFκB pathway. The molecular weight of the compound is 324.37, and its molecular formula is C₁₉H₂₀N₂O₃.

Molecular Weight

324.37

Molecular Formula

C₁₉H₂₀N₂O₃

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 61 mg/mL (188.05 mM); Water: insoluble; Ethanol: 61 mg/mL (188.05 mM); In vivo: 0.5% CMC, 6 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Bindarit can be studied extensively for its potential therapeutic applications in the treatment of chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis, by reducing the recruitment of inflammatory cells to sites of injury.