Properties
Description
Blonanserin, insoluble in DMSO and water and soluble in ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2, and dopamine D2 receptor.
Molecular Formula
C23H30FN3
Targets
5-HT2: 3.98 nM (Ki); Dopamine D2 receptor: 14.8 nM (Ki)
Solubility
DMSO: insoluble; Water: insoluble; Ethanol: 5%TFA:2.95 mg/mL (8.01 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Blonanserin can be used to block certain neurotransmitters in the brain, specifically dopamine and serotonin receptors, which help to regulate mood and behavior in individuals with schizophrenia.
Storage
Store at -20°C, and keep desiccated.
