Properties
Description
Blonanserin, insoluble in DMSO and water and soluble in ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2, and dopamine D2 receptor.
Molecular Formula
C23H30FN3
Targets
5-HT2: 3.98 nM (Ki); Dopamine D2 receptor: 14.8 nM (Ki)
Solubility
DMSO: insoluble; Water: insoluble; Ethanol: 5%TFA:2.95 mg/mL (8.01 mM)
Applications
Blonanserin can be used to block certain neurotransmitters in the brain, specifically dopamine and serotonin receptors, which help to regulate mood and behavior in individuals with schizophrenia.
