Properties
Description
PTC-209, soluble in DMSO and insoluble in ethanol and water, is compounds that target and inhibit the BMI-1 protein, which plays a critical role in cell proliferation and self-renewal, making them potential candidates for cancer therapy. It targets BMI-1 (HEK293T cells).
Molecular Formula
C17H13Br2N5OS
Targets
BMI-1 (HEK293T cells): 0.5 μM
Solubility
DMSO: 92 mg/mL (185.78 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
PTC-209 can be used to inhibit BMI-1, offering insights into stem cell biology and cancer therapy.
