Properties
Description
BMS-708163 (avagacestat), soluble in DMSO and insoluble in water and ethanol, inhibits the activity of proteases, which are enzymes involved in the breakdown of proteins. It targets γ secretase(Aβ40), and γ secretase(Aβ42).
Molecular Formula
C20H17ClF4N4O4S
Targets
γ Secretase (Aβ40): 0.3 nM; γ Secretase (Aβ42): 0.27 nM
Solubility
DMSO: 90 mg/mL (172.78 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BMS-708163 (avagacestat) can be studied for its significant potential to act as an effective antiviral agent to prevent viral infections.
Storage
Store at -20℃, and keep desiccated.
