Properties
Description
Bosentan Hydrate, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins.
Molecular Formula
C27H29N5O6S·H2O
Solubility
DMSO: 92 mg/mL (161.51 mM); Water: insoluble; Ethanol: 2 mg/mL (3.51 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Bosentan hydrate can be used for its ability to alleviate the vasoconstriction and remodeling of blood vessels in the lungs associated with CTEPH, leading to improved hemodynamics and exercise tolerance.
Storage
Store at -20°C, and keep desiccated.
