Properties
Description
Bosentan inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets ET-A, and ET-B.
Molecular Formula
C27H29N5O6S
Targets
ET-A: 4.7 nM (Ki); ET-B: 95 nM (Ki)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Bosentan can be used to helps improve exercise capacity and delay disease progression in patients with PAH.
Storage
Store at -20℃, and keep desiccated.
