Properties
Description
BRL-15572 dihydrochloride, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1A, 5-HT2B, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7.
Molecular Formula
C25H29Cl3N2O
Targets
5-HT1A: 7.7 (pki); 5-HT2B: 7.4 (pki); 5-HT1B: 6.1 (pki); 5-HT1D: 7.9 (pki); 5-HT1E: 5.2 (pki); 5-HT1F: 6 (pki); 5-HT2A: 6.6 (pki); 5-HT2C: 6.2 (pki); 5-HT6: 5.9 (pki); 5-HT7: 6.3 (pki)
Solubility
DMSO: 89 mg/mL (185.46 mM); Water: insoluble; Ethanol: 37 mg/mL (77.1 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BRL-15572 dihydrochloride can be used to modulate dopamine signaling pathways and potentially influence conditions associated with dopamine dysregulation.
Storage
Store at -20°C, and keep desiccated.
