Properties
Description
ARQ 531, soluble in DMSO and ethanol and insoluble in water, is a compound designed to block Bruton’s tyrosine kinase (BTK), an enzyme essential for the proliferation and survival of certain cancerous B cells.
Molecular Formula
C25H23ClN4O4
Solubility
DMSO: 86 mg/mL (179.56 mM); Water: Insoluble; Ethanol: 6 mg/mL (12.52 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
ARQ 531 is utilized to investigate its efficacy in overcoming resistance to first-generation BTK inhibitors in B-cell malignancies.
