BTK inhibitor CGI1746, Purity ≥98%

Synonym: 910232-84-7; BTK inhibitor; CGI 1746; CGI-1746

MDL: MFCD18782602
CAS Number: 910232-84-7
Compound CID: 24857323

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

CGI1746, soluble in DMSO and warmed ethanol and insoluble in water, is a compound designed to block Bruton’s tyrosine kinase (BTK), an enzyme essential for the proliferation and survival of certain cancerous B cells.

Molecular Weight

579.7

Molecular Formula

C₃₄H₃₇N₅O₄

Form

Lyophilized powder

Purity

Solubility

DMSO: 91 mg/mL (156.98 mM); Water: Insoluble; Warmed ethanol: 30 mg/mL (51.75 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

CGI1746 is explored for its efficacy in blocking BTK activity, contributing to potential treatments for conditions like chronic lymphocytic leukemia.