Properties
Description
CGI1746, soluble in DMSO and warmed ethanol and insoluble in water, is a compound designed to block Bruton’s tyrosine kinase (BTK), an enzyme essential for the proliferation and survival of certain cancerous B cells.
Molecular Formula
C34H37N5O4
Solubility
DMSO: 91 mg/mL (156.98 mM); Water: Insoluble; Warmed ethanol: 30 mg/mL (51.75 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
CGI1746 is explored for its efficacy in blocking BTK activity, contributing to potential treatments for conditions like chronic lymphocytic leukemia.
