Properties
Description
RN486, soluble in warmed DMSO and insoluble in water and ethanol, is a compound designed to block Bruton’s tyrosine kinase (BTK), an enzyme essential for the proliferation and survival of certain cancerous B cells. It targets BTK.
Molecular Formula
C35H35FN6O3
Solubility
Warmed DMSO: 61 mg/mL (100.54 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
RN486 is employed in studies concerning BTK’s role in immune cell signaling and its potential as a therapeutic target.