β-(1,3)-glucan is a linear glycan structure composed of glucose units connected by β-(1,3) bonds, which plays an important structural and functional role in the C. albicans cell wall and is responsible for providing cell wall strength and stability. Additionally, the immune system recognizes and responds to the presence of C. albicans β-(1,3)-glucan, which activates immune responses by interacting with specific receptors on host immune cells, such as the dectin-1 receptor, which recognizes and binds to β-(1,3)-glucan, triggering signaling pathways that lead to inflammatory responses and activation of immune cells. Therefore, C. albicans β-(1,3)-glucan is of great significance in the field of immunology and antifungal drug development and may be used as a vaccine candidate, immune adjuvant, or drug target.
CD BioGlyco provides high-quality, and high-purity C. albicans β-(1,3)-glucan production services, which are achieved through the following steps. C. albicans β-(1,3)-glucan is an important material for antifungal vaccine development.
Cultivation and fermentation of C. albicans are carried out in the culture medium under appropriate temperature, pH, and nutritional conditions to produce large quantities of cells.
The cell wall containing β-(1,3)-glucan is extracted from cultured C. albicans thallus by physical and chemical methods such as cell disruption and lysis.
The β-(1,3)-glucan in the extracted cell walls is separated through a series of separation and purification steps (such as precipitation, filtration, centrifugation, chromatography, and concentration).
Structural analysis of purified β-(1,3)-glucan samples is performed to determine their chemical and physical properties. Moreover, quality control testing is performed to ensure sample purity, stability, and integrity.
In addition, CD BioGlyco provides manufacturing for bulk production of C. albicans β-(1,3)-glucan to meet the needs of clinical trials or commercial production. C. albicans β-(1,3)-glucan acts as an immune enhancer for vaccine development. We have established a highly efficient Glyco™ Vaccine Development Platform, and we combine purified β-(1,3)-glucan with target antigens, which enhance immunogenicity and trigger stronger immune responses, helping to improve the effectiveness and protection of vaccines.
Fig.1 C. albicans β-(1,3)-glucan production services. (CD BioGlyco)
CD BioGlyco has a professional team with professional knowledge and experience in the field of C. albicans β-(1,3)-glucan production, who provide efficient and mature production services. Please feel free to contact us promptly if you are interested in our production services.
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