c-FMS inhibitor PLX647, Purity ≥98%

Synonym: 873786-09-5; c-FMS inhibitor; PLX-647; PLX 647

MDL: MFCD28100808
CAS Number: 873786-09-5
Compound CID: 11545419

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

PLX647 blocks the activity of the colony-stimulating factor-1 receptor (CSF1R), also known as c-FMS, which is implicated in various pathological conditions including certain cancers and inflammatory diseases by modulating macrophage recruitment and function.

Molecular Weight

382.38

Molecular Formula

C₂₁H₁₇F₃N₄

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

PLX647 is used in scientific studies focusing on the inhibition of c-FMS, aiding in the exploration of its role in cancer and inflammatory diseases by blocking macrophage recruitment and activation.