c-MET inhibitor AMG 208, Purity ≥98%

Synonym: 1002304-34-8; c-MET inhibitor; AMG208; AMG-208

CAS Number: 1002304-34-8
Compound CID: 24864821

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AMG 208, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets c-Met.

Molecular Weight

383.4

Molecular Formula

C₂₂H₁₇N₅O₂

Targets

c-Met: 9 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 0.22 mg/mL (0.57 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AMG 208 functions as a c-MET inhibitor in research aiming to disrupt cancer cell proliferation and survival pathways.