Properties
Description
AMG 337, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis.
Molecular Formula
C23H22FN7O3
Solubility
DMSO: 92 mg/mL (198.5 mM); Water: Insoluble; Ethanol: 92 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMG 337 is utilized as a c-MET inhibitor in cancer research, focusing on its role in tumor growth and metastasis.
